What is on the five-year horizon for higher education institutions? Which trends and technology developments will drive educational change? What are the critical challenges and how can we strategize solutions? These questions regarding technology adoption and educational change steered the discussions of 78 experts to produce the NMC Horizon Report: 2017 Higher Education Edition. The NMC Horizon Project charts the six key trends, six significant challenges, and six developments in education technology poised to impact teaching, learning, and creative inquiry in higher education.